Use of antifungals in agriculture may increase resistance in an infectious yeast

Genomic changes in the infectious yeast Candida tropicalis may play a role in its resistance to antifungals, according to a study published in PLOS Biology. The work, led by Guanghua Huang at Fudan University, China, and colleagues, shows that these genomic changes can be brought on by a common antifungal, TBZ. The study demonstrates that the use of TBZ in agriculture may contribute to the increasing problem of antifungal resistance.

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